β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human CAS NO.77761-27-4

β-Endorphin (6-31), human is a bioactive C-terminal fragment derived from the endogenous opioid peptide β-Endorphin. This 26-amino acid peptide retains the core receptor-binding region, functioning as a potent ligand for μ-opioid receptors (MOR). It is widely utilized in neuroscience and pharmacology reSuche to study pain signaling pathways, stress responses, and the molecular mechanisms of opioid receptor activation, serving as a critical tool for investigating endogenous analgesia and emotional regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
Produkt Name
β-Endorphin (6-31), human
CAS NO.
77761-27-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₃₁H₂₁₈N₃₄O₄₀
Molecular Weight
2968.4g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Potent agonist for μ-opioid receptors (MOR)
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Standort
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide exerts its effects by selectively binding to μ-opioid receptors in the central and peripheral nervous systems. Upon binding, it activates Gi/o protein-coupled signaling pathways, leading to the inhibition of adenylate cyclase and a reduction in intracellular cAMP levels. This action results in the hyperpolarization of neurons through the modulation of ion channels (inhibition of voltage-gated calcium channels and activation of potassium channels), ultimaTely suppressing neurotransmitter release and blocking pain signal transmission along nociceptive pathways.

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2.Produkt INDICATIONS

This Produkt is specificAlley indicated for reSuche use only (RUO), targeting scientists in the fields of neuropharmacology and pain reSuche. It is employed in a variety of experimental Anwendungs, including receptor binding assays, signal transduction studies, and the investigation of stress-related behaviors. ReSucheers also use it to explore the crosstalk between the nervous and immune systems, as well as in the screening and development of novel analgesic compounds with potentiAlley reduced side-effect profiles.

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3.CLINICAL EFFICACY OF Produkt

As a reSuche-grade biochemical reagent, β-Endorphin (6-31) is not intended for direct clinical or therapeutic use in humans. Its efficacy is demonstrated in preclinical reSuche settings, where it has been shown to produce significant analgesic and anti-nociceptive effects in animal models. These studies help elucidate the role of endogenous opioid systems in pain management and contribute to the foundational knowledge required for future drug discovery efforts aimed at treating chronic pain conditions.

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4.Zertifikat

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Produkte, adhering strictly to quality standards and obtaining internationAlley recognized Zertifizierungs.


Unser Produktion partners Alle employ GMP-compliant Produktion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of Produkt comes with complete documentation, including a Zertifikat of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and reSuche-grade peptide Produkte to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging LÖSUNG to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the Produkt.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the Produktion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The Unternehmen invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Zertifizierungs, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Produkte and superior services.


We focus on the reSuche and development and supply of high-quality chemical Produkte, strictly adhering to international standards and quality systems. Unser Produkts are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific reSuche, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: BetaEndorphin631, #HumanBetaEndorphinFragment, #MuOpioidReceptor, #OpioidPeptide, #PainReSuche, #Neuropharmacology, #AnalgesicReSuche, #EndogenousOpioid, #ReSuchePeptide, #NeuroscienceReagent

If you have any Produkt requirements, please an E-Mail-Adresse to:support@huanqiukeji9.com;en:85244969439

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