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[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] α-Neo-Endorphin (1-7) is a synthetic heptapeptide analog derived from the endogenous opioid α-Neoendorphin, featuring key amino acid substitutions at positions 5, 6, and 7 (Met, Lys, Lys). This modification is designed to enhance peptide stability and alter receptor interaction profiles compared to the native sequence. It is primarily utilized in biochemical reSuche as a tool compound for investigating opioid receptor signaling, structure-activity relationships (SAR), and pain modulation pathways, strictly for reSuche purposes.

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TECHNICAL SPECIFICATIONS

Item	Specification
Produkt Name	[Met5, Lys6,7] a-Neo-Endorphin (1-7)
CAS NO.	80237-40-7
Appearance	White to off-white lyophilized powder
Molecular Formula	C₃₉H₅₉N₉O₉S
Molecular Weight	849.0g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin	≤1 EU/mg
Biological Activity	Potent agonist for mu and kappa opioid receptors; modulates pain perception and neurotransmitter release
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Standort	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide retains the conserved N-terminal Tyr-Gly-Gly-Phe motif essential for opioid receptor engagement. It functions as a ligand for G protein-coupled opioid receptors (primarily μ and κ subtypes), activating inhibitory G proteins upon binding. This interaction triggers a cascade that reduces adenylate cyclase activity and cAMP Produktion, leading to neuronal hyperpolarization and inhibition of neurotransmitter release, which underlies its potential modulatory effects on pain perception and neuronal excitability.

2.Produkt INDICATIONS

This Produkt is indicated for ReSuche Use Only (RUO), targeting academic institutions, pharmaceutical R&D departments, and biotech reSucheers focused on neuropharmacology. It is applied in in vitro receptor binding assays, functional cell-based studies, and animal model experiments to elucidate the role of opioid systems in analgesia, addiction, and neuropsychiatric disorders. It is not intended for diagnostic or therapeutic use in humans.

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3.CLINICAL EFFICACY OF Produkt

While not approved for clinical use, experimental data from preclinical studies suggest that this analog exhibits bioactive properties characteristic of opioid peptides, including potential analgesic and behavioral effects in animal models. Its efficacy is primarily demonstrated in reSuche settings for validating receptor targets and screening novel therapeutic candidates, with no established human clinical trial data.

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4.Zertifikat

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Produkte, adhering strictly to quality standards and obtaining internationAlley recognized Zertifizierungs.

Unser Produktion partners Alle employ GMP-compliant Produktion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of Produkt comes with complete documentation, including a Zertifikat of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and reSuche-grade peptide Produkte to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging LÖSUNG to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the Produkt.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the Produktion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The Unternehmen invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Zertifizierungs, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Produkte and superior services.

We focus on the reSuche and development and supply of high-quality chemical Produkte, strictly adhering to international standards and quality systems. Unser Produkts are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific reSuche, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Met5Lys6,7AlphaNeoEndorphin, #AlphaNeoendorphinAnalog, #OpioidPeptide, #KappaOpioidReceptor, #MuOpioidReceptor, #PainReSuche, #NeuropharmacologyReagent, #SyntheticOpioid, #ReSuchePeptide, #StructureActivityRelationship, #AnalgesiaReSuche, #GPCRAgonist, #NeuroscienceTool, #RUOPeptide, #BiochemicalReagent

If you have any Produkt requirements, please an E-Mail-Adresse to:support@huanqiukeji9.com;en:85244969439

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